Studies on glycoprotein-derived carbohydrates.

Evaluating the Effects of Cytomegalovirus Glycoprotein B on the Maturation and Function of Monocyte-derived dendritic cells

Background & Objectives: Interaction of cytomegalovirus glycoprotein B with toll-like receptors of dendritic cells leads to early signaling and innate immune responses. The aim of this study is to evaluate the effects of cytomegalovirus glycoprotein B on the maturation and function of monocyte-derived dendritic cells in treated groups in comparison with control groups. Materials & Methods: Bloo...

Immunogenicity and Efficacy of Baculovirus Derived Glycoprotein D of Herpes Simplex Virus Type-I in Mice

Effects of Salinispora derived metabolites against multidrug resistance, an in-silico study

Background: Multidrug resistance (MDR) is known to defeat most chemotherapies as one of the main anticancer strategies. The role of overexpression/overactivation of ABC transporters, especially P-glycoprotein (P-gp), in the development of chemotherapy has long been demonstrated. Salinispora is a marine actinomycete genus known for the production of novel bioactive metabolites. Methods: In this...

Protein Digestion-Derived Peptides and the Peripheral Regulation of Food Intake

The gut plays a central role in energy homeostasis. Food intake regulation strongly relies on the gut-brain axis, and numerous studies have pointed out the significant role played by gut hormones released from enteroendocrine cells. It is well known that digestive products of dietary protein possess a high satiating effect compared to carbohydrates and fat. Nevertheless, the processes occurring...

Low-fat, high-sugar diet and lipoprotein profiles.

The recent paper by Dreon et al (1) reported that a very-lowfat diet is not associated with improved lipoprotein profiles in men. The dietary nutrient data presented in their Table 1 show that at the same time that the percentage of energy from fat decreased from 31.8% to 10.4%, that from carbohydrates increased from 52.1% to 75.7%, with half of the carbohydrate energy derived from simple sugar...

Sheep conceptuses from day 16 of pregnancy were cultured in the presence of [3Hlglucosamine and [14C]leucine and a high-molecular-weight glycoprotein (HMWG) secreted into the culture medium was purified by a combination of anion-exchange and gel filtration chromatography. The HMWG

Sheep conceptuses from day 16 of pregnancy were cultured in the presence of [3Hlglucosamine and [14C]leucine and a high-molecular-weight glycoprotein (HMWG) secreted into the culture medium was purified by a combination of anion-exchange and gel filtration chromatography. The HMWG was found to have a molecular weight between 800 000 and 900 000 and to be highly resistant to digestion with prona...